The plaque, which was unveiled in Tyers Gate last month, is the fruit of research by local historian Jennie Howells.
Jonathan Tyers was born on Bermondsey Street in 1702 to a family of wool-staplers.
He is best known as the manager of Vauxhall Pleasure Gardens which he operated from 1728 and turned into a fashionable place of entertainment.
After his death in 1767 Tyers was buried in St Mary Magdalen Church.
The family name persists in Bermondsey at the 1930s-built Tyers Estate and on the street known as Tyers Gate which links Bermondsey Street with Leathermarket Gardens.
In Vauxhall, Tyers has two streets named after him: Jonathan Street and Tyers Street.
The plaque has been funded by Leathermarket JMB and Southwark Council.